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Vital Nutrients 5HTP 100mg 5HTP (5-Hydroxytryptophan) is made in the body from L-tryptophan, and can be converted to serotonin. 5-HTP readily crosses the blood-brain barrier, and promotes serotonin levels in the brain which help create healthy functioning of the sleep/wake cycle and positive mood. Along with emotional well-being, appetite control may also be affected in a positive manner. Vital Nutrients 5HTP is naturally derived from the seeds of the Griffonia simplificolia plant.